The present invention is to provide a folding knife, which includes a handle provided therein with first and second slots, wherein the first slot extends slantingly from a first end toward a second end of the handle; a pushing element formed with a third slot slantingly extending in a direction opposite to the first slot and at least one post; and a pressing element having one end pivotally provided in the handle and another end provided with at least one sliding block capable of moving in the first and third slots and an abutting portion capable of abutting against the blade. When the pushing element is pushed, the post moves along the second slot and drives the sliding block to move along the first and third slots, thereby enabling the abutting portion to apply force to the blade and rotate the blade out of the handle to a predetermined angle.