Invention Grant
US09303035B2 Substituted pyrazino[1′,2′:1,2]pyrrolo[3,4-d]pyrimidines, pyrimido[4′,5′:3,4]pyrrolo[2,1-c][1,4]oxazines and pyrimido[4′,5′:3,4]pyrrolo[1,2-d][1,4]oxazepines for inhibiting the CFTR channel
有权
取代的吡嗪并[1'，2'：1,2]吡咯并[3,4-d]嘧啶，嘧啶并[4'，5'：3,4]吡咯并[2,1-c] [1,4] 嘧啶并[4'，5'：3,4]吡咯并[1,2-d] [1,4]氧氮杂用于抑制CFTR通道
![Substituted pyrazino[1′,2′:1,2]pyrrolo[3,4-d]pyrimidines, pyrimido[4′,5′:3,4]pyrrolo[2,1-c][1,4]oxazines and pyrimido[4′,5′:3,4]pyrrolo[1,2-d][1,4]oxazepines for inhibiting the CFTR channel](/docs/US/2016-04-05/US09303035B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted pyrazino[1′,2′:1,2]pyrrolo[3,4-d]pyrimidines, pyrimido[4′,5′:3,4]pyrrolo[2,1-c][1,4]oxazines and pyrimido[4′,5′:3,4]pyrrolo[1,2-d][1,4]oxazepines for inhibiting the CFTR channel
- Patent Title (中): 取代的吡嗪并[1'，2'：1,2]吡咯并[3,4-d]嘧啶，嘧啶并[4'，5'：3,4]吡咯并[2,1-c] [1,4] 嘧啶并[4'，5'：3,4]吡咯并[1,2-d] [1,4]氧氮杂用于抑制CFTR通道
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Application No.: US14109927Application Date: 2013-12-17
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Publication No.: US09303035B2Publication Date: 2016-04-05
- Inventor: Mahbub Ahmed , Alexander Ashall-Kelly , Graham Charles Bloomfield , Louisa Gueritz , Jeffrey McKenna , Joseph McKenna , Simon Mutton , Rakesh Parmar , Jon Sheperd , Paul Wright
- Applicant: Mahbub Ahmed , Alexander Ashall-Kelly , Graham Charles Bloomfield , Louisa Gueritz , Jeffrey McKenna , Joseph McKenna , Simon Mutton , Rakesh Parmar , Jon Sheperd , Paul Wright
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Jing Grace Sun
- Main IPC: A61K31/519
- IPC: A61K31/519 ; C07D239/70 ; C07D487/14 ; A61K31/5383 ; A61K31/553 ; A61K45/06 ; C07D498/14
![Substituted pyrazino[1′,2′:1,2]pyrrolo[3,4-d]pyrimidines, pyrimido[4′,5′:3,4]pyrrolo[2,1-c][1,4]oxazines and pyrimido[4′,5′:3,4]pyrrolo[1,2-d][1,4]oxazepines for inhibiting the CFTR channel](/abs-image/US/2016/04/05/US09303035B2/abs.jpg.150x150.jpg)
Abstract:
The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof; and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Public/Granted literature
- US20140171412A1 TRICYCLIC COMPOUNDS Public/Granted day:2014-06-19
Information query
IPC分类:
