Invention Grant
- Patent Title: Spirooxindole derivative and process for producing the same
- Patent Title (中): 螺氧基吲哚衍生物及其制备方法
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Application No.: US14431935Application Date: 2013-10-04
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Publication No.: US09309261B2Publication Date: 2016-04-12
- Inventor: Hai-Lei Cui , Fujie Tanaka
- Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION
- Applicant Address: JP Okinawa
- Assignee: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION
- Current Assignee: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION
- Current Assignee Address: JP Okinawa
- Agency: Chen Yoshimura LLP
- International Application: PCT/JP2013/077682 WO 20131004
- International Announcement: WO2014/058035 WO 20140417
- Main IPC: C07D491/107
- IPC: C07D491/107 ; A61K31/407
Abstract:
Disclosed is a compound of formula I: wherein R1?, R2?, R3?, R4?, R5?, n and m are defined herein. The compound of formula I is prepared by a concise, catalytic enantioselective formal hetero-Diels-Alder (hDA) reactions of enones with isatins and is useful for making pharmaceutical composition for the treatment of proliferative diseases.
Public/Granted literature
- US20150246927A1 NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME Public/Granted day:2015-09-03
Information query
