Embodiments of the present invention generally relate to data processing, and further the embodiments of the invention relate to a method of processing a visible coding sequence and a system thereof, a method of playing a visible coding sequence and a system thereof. The present invention creatively proposes a scheme of determining sampling rate with synchronized frames to realize effective processing of a visible coding sequence. The scheme of processing a visible coding sequence according to the invention is helpful for visible coding synchronization on the capturing side, enabling the capturing side to determine appropriate sampling rate and sampling timing, and thus effectively acquire the visible coding sequence, which may not only reduce resource waste, but also acquire a complete visible coding sequence.