The present invention discloses an electrophoretic display and a driving met hod thereof, comprising: arranging each pixel electrode in the electrophoretic display to correspond to a pixel; determining a driving waveform of the electrophoretic display based on the initial gray level and the final gray level of the pixel, applying a display signal of the driving waveform to the pixel electrode, controlling the pixel whose gray level value needs to be changed; wherein the driving waveform comprises at least one gray level driving procedure, each driving procedure corresponds to a gray level changing direction, the final gray level is a gradually changing gray level in the gray level changing direction which the last driving procedure corresponds to. The present invention can realize relatively accurate control to the gray level change while keeping DC balance by means of the electrophoretic display and the driving method thereof when the screen is refreshed.