A method and system is disclosed for dynamic swapping of uplink and downlink base stations. A user equipment device (UE) may engage in a communication session with a downlink from a first base station (e.g., eNodeB) and an uplink to second, different base station. If a determination is made that more favorable operating conditions for transmitting session communications to the UE are available on a downlink air interface from the second base station than on the downlink air interface from the first base station, the uplink and downlink may be swapped, such that after swapping, the UE may have a downlink from second base station and an uplink to the first base station.