Invention Grant
- Patent Title: Anti-malarial compositions
- Patent Title (中): 抗疟剂组合物
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Application No.: US14097799Application Date: 2013-12-05
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Publication No.: US09321834B2Publication Date: 2016-04-26
- Inventor: Gabriel M. Gutierrez , James Pannucci , Amy Noe , Steve Chienwen Huang , Scott Winram , Annie Xiaoyan Mo
- Applicant: Leidos, Inc. , The United States of America, as represented by the Secretary, Dept. of Health and Human Services
- Applicant Address: US VA Reston US DC Washington
- Assignee: LEIDOS, INC.,THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
- Current Assignee: LEIDOS, INC.,THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
- Current Assignee Address: US VA Reston US DC Washington
- Agency: Banner & Witcoff, Ltd.
- Main IPC: A61K39/015
- IPC: A61K39/015 ; A61K45/00 ; A61K39/395 ; C07K16/20 ; A61K45/06 ; A61K39/00
Abstract:
This disclosure provides antibodies that are useful for preventing and/or treating malaria. The epitope to which the antibodies bind is in close proximity to the conserved proteolytic cleavage site of P. falciparum circumsporozoite protein (CSP), and the antibodies provided in this disclosure can prevent cleavage and inhibit P. falciparum sporozoites from invading the liver.
Public/Granted literature
- US20150158941A1 ANTI-MALARIAL COMPOSITIONS Public/Granted day:2015-06-11
Information query
