Provided are a backplane for a flat panel display device and a method of manufacturing the backplane. The method of manufacturing the backplane for a flat panel display device includes forming an insulation substrate on a glass substrate, forming a protection layer on the insulation substrate, the protection layer including a first opening exposing a portion of the insulation substrate, forming a first hole in the insulation substrate by removing the portion of the insulation substrate exposed by the first opening, and forming a transistor on the protection layer, the transistor including an active layer, a gate electrode, a source electrode, and a drain electrode. The insulation substrate may include a transistor area including the transistor, and a non-transistor area excluding the transistor and including the first hole.