发明授权
- 专利标题: Use of lactulose in the treatment of autism
- 专利标题(中): 使用乳果糖治疗自闭症
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申请号: US14087930申请日: 2013-11-22
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公开(公告)号: US09345721B2公开(公告)日: 2016-05-24
- 发明人: Joan M. Fallon , Richard Feltenstein
- 申请人: Curemark LLC
- 申请人地址: US NY Rye
- 专利权人: Curemark, LLC
- 当前专利权人: Curemark, LLC
- 当前专利权人地址: US NY Rye
- 代理机构: Wilson Sonsini Goodrich & Rosati
- 主分类号: A61K31/7016
- IPC分类号: A61K31/7016 ; A61K35/37 ; A61K31/045 ; A61K31/7012
摘要:
A treatment for autism in which an effective amount of lactulose is administered in order to bind excess ammonia in the gastrointestinal tract, the bloodstream, and the nervous system in order to prevent or reverse ammonia poisoning caused by the administration of certain antibiotics. Lactulose molecules in the colon are fermented by certain bacteria. The fermentation process lowers the colonic pH, and ammonia, in the form of ammonium ions, is used by the bacteria for amino acid and protein synthesis. This lowers the serum ammonia levels and reduces neurotoxicity.
公开/授权文献
- US20140187512A1 USE OF LACTULOSE IN THE TREATMENT OF AUTISM 公开/授权日:2014-07-03
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