In order to provide a simple and installation-friendly design of a setting unit of a dispenser (10) for dispensing a substance consisting of at least two components from at least two containers, each having a pump unit (12a, 12b), by means of a moveable actuating device (40) for the pump units (12a, 12b) and a dispenser nozzle for the substance to be dispensed, according to the invention the setting unit (38) can be varied with respect to the distance thereof to the containers or pump units (12a, 12b), or with respect to the distance of the projections (61a, b) thereof in relation to a pivot axis (43) of the actuating device (40), in particular in opposite directions.