Invention Grant
- Patent Title: Pyrimidyl cyclopentanes as Akt protein kinase inhibitors
- Patent Title (中): 嘧啶环戊烷作为Akt蛋白激酶抑制剂
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Application No.: US13676963Application Date: 2012-11-14
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Publication No.: US09346805B2Publication Date: 2016-05-24
- Inventor: Anna Banka , Josef R. Bencsik , James F. Blake , Kin Chiu Fong , Martin F. Hentemann , Ian S. Mitchell , Douglas McCord Sammond , Tony P. Tang , Eli M. Wallace , Rui Xu , James Graham
- Applicant: Array BioPharma Inc.
- Applicant Address: US CO Boulder
- Assignee: ARRAY BIOPHARMA INC.
- Current Assignee: ARRAY BIOPHARMA INC.
- Current Assignee Address: US CO Boulder
- Agency: Viksnins Harris & Padys PLLP
- Main IPC: C07D471/10
- IPC: C07D471/10 ; C07D487/10

Abstract:
The present invention provides compounds of Formula I including tautomers, resolved enantiomers, resolved diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as Akt protein kinase inhibitors and for the treatment of Akt-mediated diseases, for example, hyperproliferative diseases such as cancer.
Public/Granted literature
- US20130072500A1 PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS Public/Granted day:2013-03-21
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