Invention Grant
US09346885B2 Method of treating type 1 diabetes with antagonist IL-7 receptor antibodies
有权
用拮抗剂IL-7受体抗体治疗1型糖尿病的方法
- Patent Title: Method of treating type 1 diabetes with antagonist IL-7 receptor antibodies
- Patent Title (中): 用拮抗剂IL-7受体抗体治疗1型糖尿病的方法
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Application No.: US14109267Application Date: 2013-12-17
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Publication No.: US09346885B2Publication Date: 2016-05-24
- Inventor: Chia-Yang Lin , Li-Fen Lee , Wenwu Zhai
- Applicant: RINAT NEUROSCIENCE CORP.
- Applicant Address: US CA South San Francisco
- Assignee: Rinat Neuroscience Corp.
- Current Assignee: Rinat Neuroscience Corp.
- Current Assignee Address: US CA South San Francisco
- Agent Susan L. Wang
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; A61K39/00
Abstract:
The present invention provides antagonizing antibodies that bind to interleukin-7 receptor (IL-7R). The invention further provides a method of obtaining such antibodies and antibody-encoding nucleic acids. The invention further relates to therapeutic methods for use of these antibodies and antigen-binding portions thereof for the treatment and/or prevention of type 2 diabetes and immunological disorders, including type 1 diabetes, multiple sclerosis, rheumatoid arthritis, graft-versus-host disease, and lupus.
Public/Granted literature
- US20140141018A1 ANTAGONIST ANTI-IL-7 RECEPTOR ANTIBODIES AND METHODS Public/Granted day:2014-05-22
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