Invention Grant
US09346902B2 Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing 3-hydroxyisobutyrate or methacrylic acid related thereto
有权
用于提高在甲醇存在下还原当量的可用性的微生物和方法，以及用于生产与其相关的3-羟基异丁酸酯或甲基丙烯酸
- Patent Title: Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing 3-hydroxyisobutyrate or methacrylic acid related thereto
- Patent Title (中): 用于提高在甲醇存在下还原当量的可用性的微生物和方法，以及用于生产与其相关的3-羟基异丁酸酯或甲基丙烯酸
-
Application No.: US14071339Application Date: 2013-11-04
-
Publication No.: US09346902B2Publication Date: 2016-05-24
- Inventor: Anthony P. Burgard , Robin E. Osterhout , Stephen J. Van Dien , Cara Ann Tracewell , Priti Pharkya , Stefan Andrae
- Applicant: Genomatica, Inc.
- Applicant Address: US CA San Diego
- Assignee: Genomatica, Inc.
- Current Assignee: Genomatica, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Jones Day
- Main IPC: C12P7/42
- IPC: C12P7/42 ; C08F120/06 ; C08G63/664 ; C12N15/63 ; C12P7/24 ; C12P7/40 ; C12N15/52
Abstract:
Provided herein is a non-naturally occurring microbial organism having a methanol metabolic pathway that can enhance the availability of reducing equivalents in the presence of methanol. Such reducing equivalents can be used to increase the product yield of organic compounds produced by the microbial organism, such as 3-hydroxyisobutyrate or MAA. Also provided herein are methods for using such an organism to produce 3-hydroxyisobutyrate or MAA.
Public/Granted literature
Information query
