发明授权
US09347101B2 Methods of diagnosing or treating prostate cancer using the ERG gene, alone or in combination with other over or under expressed genes in prostate cancer
有权
使用ERG基因诊断或治疗前列腺癌的方法，单独或与前列腺癌中其他过表达或低表达基因组合
- 专利标题： Methods of diagnosing or treating prostate cancer using the ERG gene, alone or in combination with other over or under expressed genes in prostate cancer
- 专利标题（中）： 使用ERG基因诊断或治疗前列腺癌的方法，单独或与前列腺癌中其他过表达或低表达基因组合
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申请号： US13756028申请日： 2013-01-31
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公开(公告)号： US09347101B2公开(公告)日： 2016-05-24
- 发明人: Gyorgy Petrovics , Shiv Srivastava
- 申请人： The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
- 申请人地址： US MD Bethesda
- 专利权人： The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
- 当前专利权人： The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
- 当前专利权人地址： US MD Bethesda
- 代理机构： MH2 Technology Law Group, LLP
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C07K16/30
摘要：
The present invention relates to oncogenes or tumor suppressor genes, as well as other genes, involved in prostate cancer and their expression products, as well as derivatives and analogs thereof. Provided are therapeutic compositions and methods of detecting and treating cancer, including prostate and other related cancers. Also provided are methods of diagnosing and/or prognosing prostate cancer by determining the expression level of at least one prostate cancer-cell-specific gene, including, for example, the ERG gene or the LTF gene alone, or in combination with at least one of the AMACR gene and the DD3 gene.