发明授权
- 专利标题： Stabilized liquid and lyophilized ADAMTS13 formulations
- 专利标题（中）： 稳定的液体和冻干的ADAMTS13制剂
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申请号： US14088169申请日： 2013-11-22
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公开(公告)号： US09351935B2公开(公告)日： 2016-05-31
- 发明人: Peter Matthiessen , Peter L. Turecek , Hans-Peter Schwarz
- 申请人： Baxter International Inc. , Baxter Healthcare S.A.
- 申请人地址： US IL Bannockburn CH Glattpark (Opfikon)
- 专利权人： Baxalta Incorporated,Baxalta GmbH
- 当前专利权人： Baxalta Incorporated,Baxalta GmbH
- 当前专利权人地址： US IL Bannockburn CH Glattpark (Opfikon)
- 代理机构： Morgan, Lewis & Bockius LLP
- 主分类号： C12N9/00
- IPC分类号： C12N9/00 ; A61K38/00 ; A61K9/19 ; A61K9/08 ; A61K38/48 ; A61K47/02 ; A61K47/10 ; A61K47/18 ; A61K47/26 ; A61K9/00
摘要：
The present invention relates to formulations of ADAMTS13 with enhanced or desirable properties. As such, the invention provides liquid and lyophilized formulations of ADAMTS13 that are suitable for pharmaceutical administration. Among other aspects, the present invention also provides methods of treating various diseases and conditions related to VWF and/or ADAMTS13 dysfunction in a subject. Also provided herein are kits comprising ADAMTS13 formulations useful for the treatment of various diseases and conditions.
公开/授权文献
- US20140178357A1 STABILIZED LIQUID AND LYOPHILIZED ADAMTS13 FORMULATIONS 公开/授权日：2014-06-26
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