发明授权
- 专利标题： Compositions and methods to enhance the immune system
- 专利标题（中）： 组合和增强免疫系统的方法
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申请号： US14153714申请日： 2014-01-13
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公开(公告)号： US09352037B2公开(公告)日： 2016-05-31
- 发明人: Timo Kars van den Berg
- 申请人： Timo Kars van den Berg
- 申请人地址： NL Amsterdam
- 专利权人： STICHTING SANQUIN BLOEDVOORZIENING
- 当前专利权人： STICHTING SANQUIN BLOEDVOORZIENING
- 当前专利权人地址： NL Amsterdam
- 代理机构： Hoffmann & Baron, LLP
- 优先权： EP08155011 20080423
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61K39/275 ; C07K16/30 ; A61K39/12 ; C07K16/28 ; A61K39/00
摘要：
The invention relates to the field of molecular medicine. In particular, it relates to compositions and methods to enhance the clearance of aberrant cells, e.g. cancer cells or virus-infected cells, by the host's immune system. Provided is a composition comprising (i) a therapeutic compound that can trigger a host's immune effector cells against an aberrant cell, such as a therapeutic antibody, and (ii) at least one agent capable of reducing or preventing inhibitory signal transduction initiated via SIRPalpha.
公开/授权文献
- US20140199308A1 COMPOSITIONS AND METHODS TO ENHANCE THE IMMUNE SYSTEM 公开/授权日：2014-07-17
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