发明授权
- 专利标题: Method for manufacturing isothiazole compound
- 专利标题(中): 异噻唑化合物的制备方法
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申请号: US14432589申请日: 2013-10-04
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公开(公告)号: US09353071B2公开(公告)日: 2016-05-31
- 发明人: Takashi Abe
- 申请人: IHARA CHEMICAL INDUSTRY CO., LTD.
- 申请人地址: JP Tokyo
- 专利权人: IHARA CHEMICAL INDUSTRY CO., LTD.
- 当前专利权人: IHARA CHEMICAL INDUSTRY CO., LTD.
- 当前专利权人地址: JP Tokyo
- 代理机构: Bacon & Thomas, PLLC
- 优先权: JP2012-223321 20121005
- 国际申请: PCT/JP2013/005925 WO 20131004
- 国际公布: WO2014/054294 WO 20140410
- 主分类号: C07D275/03
- IPC分类号: C07D275/03 ; C07D275/02
摘要:
An industrially preferred process for producing an isothiazole compound, particularly 3,4-dichloro-5-cyanoisothiazole, provides a safer industrial production process by avoiding the simultaneous use of an aprotic polar solvent such as N,N-dimethylformamide and chlorine. In addition, a production process which is economically preferred because an aprotic polar solvent, which is highly likely to become a part of waste, is not used.A process for producing an isothiazole compound represented by a general formula (3), wherein R is a cyano group or the like; and X is a chlorine atom or the like, which comprises heating a nitrile compound represented by a general formula (1), wherein R is as defined above, and sulfur, and then carrying out a reaction between the nitrile compound represented by the general formula (1), the sulfur and a halogen represented by a general formula (2), wherein X is as defined above.
公开/授权文献
- US20150291540A1 METHOD FOR MANUFACTURING ISOTHIAZOLE COMPOUND 公开/授权日:2015-10-15
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