Invention Grant
- Patent Title: Tetrahydrocarboline derivative
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Application No.: US14005062Application Date: 2012-01-05
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Publication No.: US09353113B2Publication Date: 2016-05-31
- Inventor: Akira Ohata , Shingo Nakatani , Tetsuya Sugiyama , Takashi Morimoto
- Applicant: Akira Ohata , Shingo Nakatani , Tetsuya Sugiyama , Takashi Morimoto
- Applicant Address: JP Osaka
- Assignee: ONO PHARMACEUTICAL CO., LTD.
- Current Assignee: ONO PHARMACEUTICAL CO., LTD.
- Current Assignee Address: JP Osaka
- Agency: Sughrue Mion, PLLC
- Priority: JP2011-060765 20110318
- International Application: PCT/JP2012/050050 WO 20120105
- International Announcement: WO2012/127885 WO 20120927
- Main IPC: C07D471/14
- IPC: C07D471/14 ; A61K9/00 ; A61K47/26 ; A61K9/19 ; A61K9/20

Abstract:
An object of the present invention is to provide a drug having the inhibitory activity on ENPP2 which is a different target from that of the existing drug, as a medicament useful in a urinary excretion disorder patient for whom the existing drug has the insufficient effect.The present invention provides a compound represented by the general formula (I): (wherein definition of each group is as defined in the description) having the ENPP2 inhibitory activity, a salt thereof or a solvate thereof or a prodrug thereof, and an agent for preventing or treating urinary excretion disorder and/or improving symptoms thereof, containing them as an active ingredient.
Public/Granted literature
- US20130345426A1 TETRAHYDROCARBOLINE DERIVATIVE Public/Granted day:2013-12-26
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