发明授权
- 专利标题： Multimeric multiepitope influenza vaccines
- 专利标题（中）： 多聚多表位流感疫苗
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申请号： US14263359申请日： 2014-04-28
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公开(公告)号： US09353159B2公开(公告)日： 2016-05-31
- 发明人: Tamar Ben-Yedidia , Yossi Singer
- 申请人： BIONDVAX PHARMACEUTICALS LTD.
- 申请人地址： IL Ness Ziona
- 专利权人： BiondVax Pharmaceuticals Ltd.
- 当前专利权人： BiondVax Pharmaceuticals Ltd.
- 当前专利权人地址： IL Ness Ziona
- 代理机构： Winston & Strawn LLP
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; A61K39/145 ; A61K39/00 ; A61K39/12 ; A61K39/295 ; C07K14/005
摘要：
An isolated polynucleotide encoding an influenza multi-epitope polypeptide, wherein the multi-epitope polypeptide comprises multiple copies of a plurality of influenza virus peptide epitopes wherein the polypeptide is B(X1ZX2Z . . . Xm)nB or B(X1)nZ(X2)nZ . . . (Xm)nB; wherein B is an optional sequence of 1-4 amino acid residues; n is at each occurrence independently an integer of 2-50; m is an integer of 3-15; each of X1, X2 . . . Xm is an influenza peptide epitope of 4-24 amino acid residues; and Z at each occurrence is a bond or a spacer of 1-4 amino acid residues.
公开/授权文献
- US20140286982A1 MULTIMERIC MULTIEPITOPE INFLUENZA VACCINES 公开/授权日：2014-09-25
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