Radio frequency (RF) duplexing devices and methods of operating the same are disclosed. In one embodiment, an RF duplexing device includes a transmission port, a receive port, a first duplexer, and a second duplexer. The first duplexer is coupled to the transmission port and the receive port, and is configured to provide a first phase shift from the transmission port to the receive port. The second duplexer is also coupled to the transmission port and the receive port. However, the second duplexer is configured to provide a second phase shift that is differential to the first phase shift from the transmission port to the receive port. By providing the second phase shift so that the second phase shift is differential to the first phase shift, the RF duplexing device can provide isolation through cancellation without needing to introduce significant insertion losses.