Invention Grant
- Patent Title: Lipid therapy
- Patent Title (中): 脂质治疗
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Application No.: US14299771Application Date: 2014-06-09
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Publication No.: US09358268B2Publication Date: 2016-06-07
- Inventor: Deborah Kilpatrick , Syed Faiyaz Ahmed Hossainy , Irina Astafieva , Florian N. Ludwig , Paul M. Consigny , Jeffrey T. Ellis , Florencia Lim
- Applicant: Abbott Cardiovascular Systems Inc.
- Applicant Address: US CA Santa Clara
- Assignee: Abbott Cardiovascular Systems Inc.
- Current Assignee: Abbott Cardiovascular Systems Inc.
- Current Assignee Address: US CA Santa Clara
- Agency: Blakely Sokoloff Taylor & Zafman LLP
- Agent Randy Shen, Esq.
- Main IPC: A61K38/17
- IPC: A61K38/17 ; A61K9/00 ; A61K9/127 ; A61K9/16 ; A61M1/34
Abstract:
A method including introducing into a blood stream a delipidated high density lipoprotein (HDL) and a bioactive agent. A composition including a delipidated high density lipoprotein (HDL) and an auxiliary agent in a form suitable for delivery into a blood vessel. A composition including Apo A1 comprising a hydrophobic ligand suitable to interact with cell surface binding sites. A composition including Apo A1 and an agent selected to one of increase the ATP-binding cassette protein 1 (ABCA1) transporter expression in macrophages and protect ABCA1 from thiol-mediated degradation.
Public/Granted literature
- US20140287033A1 LIPID THERAPY Public/Granted day:2014-09-25
Information query
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