Invention Grant
- Patent Title: 7-substituted indole Mcl-1 inhibitors
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Application No.: US14683839Application Date: 2015-04-10
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Publication No.: US09359296B2Publication Date: 2016-06-07
- Inventor: Xilu Wang , Xiaohong Song , Steven W. Elmore , Milan Bruncko , David J. Madar , Andrew J. Souers , Lisa A. Hasvold , Le Wang , Zhi-Fu Tao , Aaron R. Kunzer
- Applicant: AbbVie Inc.
- Applicant Address: US IL North Chicago
- Assignee: ABBVIE INC.
- Current Assignee: ABBVIE INC.
- Current Assignee Address: US IL North Chicago
- Agency: Jones Day
- Main IPC: C07D401/06
- IPC: C07D401/06 ; C07D401/14 ; C07D209/42 ; A61K31/5377 ; C07D413/14 ; C07D209/34 ; C07D401/12 ; C07D413/06 ; C07D417/04 ; C07D401/04 ; C07D413/12 ; C07D405/06 ; C07D491/113
Abstract:
Compounds which inhibit the activity of anti-apoptotic Mcl-1 protein, compositions containing the compounds, and methods of treating diseases involving overexpressed or unregulated Mcl-1 protein are disclosed.
Public/Granted literature
- US20150284328A1 7-SUBSTITUTED INDOLE MCL-1 INHIBITORS Public/Granted day:2015-10-08
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