A method for performing digital predistortion to a microwave radio transceiver in response to an increase/decrease of transmit power level is disclosed. If the new transmit power level is higher than the current transmit power level, a set of digital predistortion (DPD) coefficients is applied to the transceiver before the issuance of a transmit power level increase command to the transceiver. Otherwise, a transmit power level decrease command is issued to the transceiver before the application of the set of DPD coefficients to the transceiver. Determining the set of DPD coefficients for the transceiver involves two stages: (i) calibrating the transceiver at a room temperature under predefined conditions and generating a DPD lookup table including DPD coefficients at a plurality of predefined temperatures other than the room temperature and (ii) determining the set of DPD coefficients for a given set of operating conditions using entries in the DPD lookup table.