Embodiments provide systems and methods for enabling the support of multiple Ethernet Passive Optical Network over Coax (EPoC) channels, which can be bonded together into a single high-speed channel. The multiple EPoC channels can be configured according to available spectrum, such that they occupy one or more, frequency contiguous or separated, segments of the available spectrum. The size (number of sub-carriers) of each of the channels can be configured according to embodiments based on the available spectrum and/or other requirements (e.g., EPoC emission requirements, existing services, etc.). Further, within each channel, individual sub-carriers can be configured independently, including turning each sub-carrier on/off and/or specifying the symbol bit loading for the sub-carrier independently of other sub-carriers in the channel.