发明授权
- 专利标题： Adjuvant compounds
- 专利标题（中）： 佐剂化合物
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申请号： US12304878申请日： 2007-06-15
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公开(公告)号： US09370557B2公开(公告)日： 2016-06-21
- 发明人: Timothy John Mitchell , Lea-Ann Kirkham , Graeme James Cowan , Gillian Douce
- 申请人： Timothy John Mitchell , Lea-Ann Kirkham , Graeme James Cowan , Gillian Douce
- 申请人地址： GB Glasgow
- 专利权人： The University Court of the University of Glasgow
- 当前专利权人： The University Court of the University of Glasgow
- 当前专利权人地址： GB Glasgow
- 代理机构： Dann, Dorfman, Herrell and Skillman, P.C.
- 代理商 Kathleen D. Rigaut
- 国际申请： PCT/GB2007/002242 WO 20070615
- 国际公布： WO2007/144647 WO 20071221
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K39/02 ; A61K39/12 ; A61K39/38 ; A61K45/00 ; A61K39/09
摘要：
The invention relates to the use of bacterial cytolysin proteins, such as pneumolysin, as adjuvants for stimulating or enhancing immune responses against co-administered target antigens. Desirably, the target antigen is provided as a fusion protein with the cytolysin. The inventors have found that cytolysins may be particularly effective for stimulation of mucosal immune responses against the target antigen.
公开/授权文献
- US20100166795A1 Novel Adjuvant Compounds 公开/授权日：2010-07-01
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