Invention Grant
- Patent Title: Dual-targeted therapeutic peptide for nasopharyngeal carcinoma, nanoparticles carrying same and uses thereof
- Patent Title (中): 用于鼻咽癌的双靶向治疗肽，携带其的纳米颗粒及其应用
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Application No.: US14406399Application Date: 2013-06-07
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Publication No.: US09371364B2Publication Date: 2016-06-21
- Inventor: Qingming Luo , Zhihong Zhang , Haiming Luo
- Applicant: HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
- Applicant Address: CN Wuhan, Hubei
- Assignee: HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
- Current Assignee: HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
- Current Assignee Address: CN Wuhan, Hubei
- Agency: Carter, DeLuca, Farrell & Schmidt, LLP
- Priority: CN201210185089 20120607
- International Application: PCT/CN2013/000680 WO 20130607
- International Announcement: WO2013/181934 WO 20131212
- Main IPC: A61K38/16
- IPC: A61K38/16 ; C07K14/00 ; C07K7/08 ; A61K9/51 ; A61K31/12 ; A61K31/337 ; C07K14/47 ; A61K47/48 ; A61K49/00 ; A61K38/10 ; A61K47/42
Abstract:
Disclosed is a dual-targeted therapeutic peptide for nasopharyngeal carcinoma formed by covalently linking a targeted therapeutic peptide for nasopharyngeal carcinoma, a peptide linker and a targeted therapeutic peptide with an α-helical structure for nasopharyngeal carcinoma. Also disclosed is a nanoparticle containing the peptide. The peptide and the nanoparticle can be used to treat nasopharyngeal carcinoma.
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