Invention Grant
- Patent Title: Markers associated with human double minute 2 inhibitors
- Patent Title (中): 与人类双分钟2抑制剂相关的标记物
-
Application No.: US13950881Application Date: 2013-07-25
-
Publication No.: US09371568B2Publication Date: 2016-06-21
- Inventor: Swann Gaulis , Sebastien Jeay
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent David A. Carpenter
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/00 ; G01N33/53 ; C07D401/12 ; G01N33/68 ; G01N33/574 ; A61K31/496 ; G01N33/50
Abstract:
The invention provides methods of monitoring differential gene expression of biomarkers to determine patient sensitivity to Human Double Minute inhibitors (MDM2i), methods of determining the sensitivity of a cell to an MDM2i by measuring biomarkers and methods of screening for candidate MDM2i.
Public/Granted literature
- US20140038986A1 MARKERS ASSOCIATED WITH HUMAN DOUBLE MINUTE 2 INHIBITORS Public/Granted day:2014-02-06
Information query
