The present invention discloses an apparatus for fastening an expansion card, which includes: a “[” shaped bracket, where a pair of guide rails is symmetrically disposed on two arts of the “[” shaped bracket and a pair of first connection parts is symmetrically formed, and a backplane is permanently connected to the bottom of the “[” shaped bracket, where at least one expansion card slot is disposed on the backplane; and a “]” shaped compression element for the expansion card, where a pair of sliding blocks is symmetrically formed on two arms of the “]” shaped compression element for the expansion card and a pair of second connection parts is symmetrically formed, where each sliding block is embedded in a guide rail and can be slid along the guide rail; The present invention improves convenience of assembly and maintenance of an expansion card.