Invention Grant
- Patent Title: Nano-recombinant fibrinogen for fibrin sealants
- Patent Title (中): 用于纤维蛋白封闭剂的纳米重组纤维蛋白原
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Application No.: US14551332Application Date: 2014-11-24
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Publication No.: US09381232B2Publication Date: 2016-07-05
- Inventor: Robert A. Burton
- Applicant: BAE Systems Information and Electronic Systems Integration Inc.
- Applicant Address: US NH Nashua
- Assignee: BAE Systems Information and Electronic Systems Integration Inc.
- Current Assignee: BAE Systems Information and Electronic Systems Integration Inc.
- Current Assignee Address: US NH Nashua
- Agency: Rossi, Kimms & McDowell
- Agent Daniel J. Long; Bonnie McDowell
- Main IPC: A61K38/36
- IPC: A61K38/36 ; C07K14/75 ; C12Q1/56 ; A61K47/48

Abstract:
A fibrin-based hemostatic agent suitable for both civilian and military use is disclosed. The hemostatic agent comprises (i) nanoparticles to which a plurality of Knob-A recognition sequences are attached, and (ii) coiled-coils of recombinantly-produced human fibrinogen α and chains and the γ chain globular domain. A delivery system for the hemostatic agent also is disclosed, which additionally comprises means for delivering (i) and (ii) to a wound site. The delivery means may be a CO2 canister or a shaker jet.
Public/Granted literature
- US20150157694A1 NANO-RECOMBINANT FIBRINOGEN FOR FIBRIN SEALANTS Public/Granted day:2015-06-11
Information query
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