Invention Grant
- Patent Title: Compounds useful in the synthesis of halichondrin B analogs
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Application No.: US14577417Application Date: 2014-12-19
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Publication No.: US09382262B2Publication Date: 2016-07-05
- Inventor: Atsushi Endo , Charles E. Chase , Francis G. Fang
- Applicant: Eisai R&D Management Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Clark & Elbing LLP
- Main IPC: C07D407/06
- IPC: C07D407/06 ; C07D493/04 ; C07D405/06 ; C07D405/12 ; C07D307/38

Abstract:
In general, the invention features compounds useful for the synthesis of analogs of halichondrin B, such as eribulin or pharmaceutically acceptable salts thereof, e.g., eribulin mesylate. Exemplary compounds are of formula (I), (II), or (III):
Public/Granted literature
- US20150175620A1 COMPOUNDS USEFUL IN THE SYNTHESIS OF HALICHONDRIN B ANALOGS Public/Granted day:2015-06-25
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