Lossless image compression using differential transfers may involve an image compression unit receiving image data for an image in a sequence of images and transmitting the image data such that image data for at least some image tiles is transmitted using lossy compression due to resource limitations. The image compression unit may then receive image data for a subsequent image in the sequence and determine that the image data for at least some tiles does not change relative to the image data for corresponding tiles of the previous image. The image compression unit may then transmit image data in a manner sufficient to create lossless versions of tiles for which lossily compressed image data was sent previously.