Invention Grant
- Patent Title: Tetrahydroquinoline compositions as BET bromodomain inhibitors
- Patent Title (中): 四氢喹啉组合物作为BET溴结构域抑制剂
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Application No.: US14546775Application Date: 2014-11-18
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Publication No.: US09388161B2Publication Date: 2016-07-12
- Inventor: Kenneth W. Bair , Torsten Herbertz , Goss S. Kauffman , Katherine J. Kayser-Bricker , George P. Luke , Matthew W. Martin , David S. Millan , Shawn E. R. Schiller , Adam C. Talbot
- Applicant: Forma Therapeutics, Inc.
- Applicant Address: US MA Watertown
- Assignee: Forma Therapeutics, Inc.
- Current Assignee: Forma Therapeutics, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Cooley LLP
- Agent J. Dean Farmer; Serge R. Banini
- Main IPC: C07D401/14
- IPC: C07D401/14 ; A61K31/4709 ; C07D401/04 ; A61K31/5377 ; A61K31/517 ; C07D487/04 ; A61K31/519 ; A61K45/06
Abstract:
The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula I: wherein W, X, Y, Z, R1, R2, R5, and R8 are as described herein.
Public/Granted literature
- US20150232445A1 TETRAHYDROQUINOLINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS Public/Granted day:2015-08-20
Information query
