Invention Grant
- Patent Title: Serine/threonine kinase inhibitors
- Patent Title (中): 丝氨酸/苏氨酸激酶抑制剂
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Application No.: US14011501Application Date: 2013-08-27
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Publication No.: US09388171B2Publication Date: 2016-07-12
- Inventor: Jim Blake , Huifen Chen , Mark Chicarelli , John Gaudino , Lewis Gazzard , Sam Kintz , Pete Mohr , Kirk Robarge , Jacob Schwarz , Aihe Zhou
- Applicant: Array BioPharma Inc. , Genentech, Inc.
- Applicant Address: US CA South San Francisco US CO Boulder
- Assignee: GENETECH, INC.,ARRAY BIOPHARMA INC.
- Current Assignee: GENETECH, INC.,ARRAY BIOPHARMA INC.
- Current Assignee Address: US CA South San Francisco US CO Boulder
- Agency: Viksnins Harris & Padys PLLP
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D217/22 ; C07D401/12 ; C07D401/14 ; C07D405/12 ; C07D405/14 ; A61K31/4725 ; A61K31/4375 ; A61K31/472 ; A61P35/00

Abstract:
Compounds having the formula I wherein R2, X and Z as defined herein are inhibitors of ERK kinase. Also disclosed are compositions and methods for treating hyperproliferative disorders.
Public/Granted literature
- US20140066453A1 SERINE/THREONINE KINASE INHIBITORS Public/Granted day:2014-03-06
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