Invention Grant
- Patent Title: Procaspase 3 activation by combination therapy
- Patent Title (中): Procaspase 3通过联合治疗激活
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Application No.: US14383441Application Date: 2013-03-06
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Publication No.: US09399035B2Publication Date: 2016-07-26
- Inventor: Paul J. Hergenrother , Rachel C. Botham , Timothy M. Fan , Mark J. Gilbert , Michael K. Handley , Howard S. Roth , Theodore M. Tarasow
- Applicant: Paul J. Hergenrother , Rachel C. Botham , Timothy M. Fan , Mark J. Gilbert , Michael K. Handley , Howard S. Roth , Theodore M. Tarasow
- Applicant Address: US IL Urbana US IL Champaign
- Assignee: The Board of Trustees of the University of Illinois,Vanquish Oncology, Inc.
- Current Assignee: The Board of Trustees of the University of Illinois,Vanquish Oncology, Inc.
- Current Assignee Address: US IL Urbana US IL Champaign
- Agency: Haukaas Fortius PLLC
- Agent Michael Haukaas
- International Application: PCT/US2013/029405 WO 20130306
- International Announcement: WO2013/134407 WO 20130912
- Main IPC: A61K33/24
- IPC: A61K33/24 ; A61K31/495 ; A61K31/496 ; A61K45/06 ; A61K9/00 ; A61K47/10 ; A61K9/08 ; A61K9/20 ; A61K9/48 ; A61K31/138 ; A61K31/282 ; A61K31/337 ; A61K31/553 ; A61K31/704 ; A61K31/7048 ; A61K38/05
Abstract:
The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods of use are disclosed, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells. The disclosed drug combinations can have lower neurotoxicity effects than other compounds and combinations of compounds.
Public/Granted literature
- US20150017264A1 PROCASPASE 3 ACTIVATION BY COMBINATION THERAPY Public/Granted day:2015-01-15
Information query
