A method of detecting E-line loss in a disc stack centrifuge is provided, comprising: collecting data from at least one instrument associated with the centrifuge over a specific time period; calculating one or more indicators by comparing the collected data with expected values from a normally operating centrifuge, the indicators being indicative of a start of an E-line loss event; calculating the probability of E-line loss by applying weighted voting to the indicators to yield a probability value; and activating an alert upon determination that the probability value exceeds a threshold value.