The present invention provides a method and device for calibrating antenna reciprocity via OTA in a base station of wireless network, and the method comprises: determining, based on a predefined rule, a plurality of calibrating UEs out of a plurality of UEs, and antennas, to be calibrated by the plurality of calibrating UEs, of the plurality of base stations, wherein the plurality of calibrating UEs are configured to calibrate antennas of the plurality of base stations; and calibrating, according to the determined calibration relationship, the antennas reciprocity of the plurality of base stations based on the plurality of calibrating UEs. With the method of present invention, communication channel model can be calibrated effectively so as to enhance antenna reciprocity in CoMP scenario.