Systems and methods for mitigating interference in a Local Oscillator (LO) signal generated by a Phase-Locked Loop (PLL) are disclosed. In one embodiment, a system includes a PLL and an error compensation subsystem. The PLL includes a Controlled Oscillator (CO) that provides a LO output signal based on a control signal, a phase detector that generates a phase detector output signal that is indicative of a phase error between a feedback signal that is a function of the LO output signal and a reference signal, and a loop filter that filters the phase detector output signal to provide the control signal for the CO. The error compensation subsystem applies, based on the phase detector output signal, a phase rotation to a signal derived from the LO output signal to thereby compensate for a phase error in the signal resulting from a phase error in the local oscillator output signal.