Invention Grant
- Patent Title: Pyrimidyl cyclopentanes as AKT protein kinase inhibitors
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Application No.: US14086717Application Date: 2013-11-21
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Publication No.: US09409886B2Publication Date: 2016-08-09
- Inventor: Josef Bencsik , James F. Blake , James M. Graham , Martin F. Hentemann , Nicholas C. Kallan , Ian S. Mitchell , Stephen T. Schlachter , Keith L. Spencer , Dengming Xiao , Rui Xu , Mike Welch , Jun Liang , Brian S. Safina
- Applicant: Array BioPharma Inc. , Genentech, Inc.
- Applicant Address: US CO Boulder US CA South San Francisco
- Assignee: ARRAY BIOPHARMA INC.,GENENTECH, INC.
- Current Assignee: ARRAY BIOPHARMA INC.,GENENTECH, INC.
- Current Assignee Address: US CO Boulder US CA South San Francisco
- Agency: Viksnins Harris & Padys PLLP
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D401/12 ; C07D405/14 ; C07D409/14 ; C07D413/12 ; C07D403/14 ; A61P35/02 ; A61P35/04 ; A61P29/00 ; A61P9/00 ; A61P25/28 ; A61P35/00 ; A61P25/16 ; A61P31/04 ; A61P37/06 ; A61P37/08 ; A61P17/06 ; A61P11/06
Abstract:
The present invention provides compounds of Formula I, including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
Public/Granted literature
- US20160152601A9 PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS Public/Granted day:2016-06-02
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