Invention Grant
- Patent Title: Compound for sequencing by synthesis
- Patent Title (中): 通过合成进行测序的化合物
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Application No.: US14542980Application Date: 2014-11-17
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Publication No.: US09410197B2Publication Date: 2016-08-09
- Inventor: Frank Bergmann , Dieter Heindl , Jessica Steger-Domandl
- Applicant: Roche Diagnostics Operations, Inc.
- Applicant Address: US CA Pleasanton
- Assignee: ROCHE MOLECULAR SYSTEMS INC.
- Current Assignee: ROCHE MOLECULAR SYSTEMS INC.
- Current Assignee Address: US CA Pleasanton
- Agent Olga Kay
- Priority: EP13193588 20131120
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C07H19/10 ; C07H19/20 ; C07H19/00

Abstract:
The present invention provides deoxynucleoside tri- or tetraphosphate comprising a 3′ nitrate and a detectable label covalently bound to the oxygen atom of an oxymethyl or oxyallyl or oxypropargyl substitution of a nucleobase. Such compounds provide new possibilities for future Sequencing by Synthesis technologies.
Public/Granted literature
- US20150140561A1 COMPOUND FOR SEQUENCING BY SYNTHESIS Public/Granted day:2015-05-21
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