发明授权
- 专利标题: Anti-TNF-anti-IL-17 bispecific antibodies
- 专利标题(中): 抗TNF-抗IL-17双特异性抗体
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申请号: US14195885申请日: 2014-03-04
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公开(公告)号: US09416182B2公开(公告)日: 2016-08-16
- 发明人: Barrett Allan , Andrew Lawrence Glasebrook , Jirong Lu , Ying Tang , Derrick Ryan Witcher , Donmienne Doen Mun Leung , Pia Pauliina Yachi , Andrew Charles Vendel
- 申请人: Eli Lilly and Company
- 申请人地址: US IN Indianapolis
- 专利权人: Eli Lilly and Company
- 当前专利权人: Eli Lilly and Company
- 当前专利权人地址: US IN Indianapolis
- 代理商 Gregory A. Cox
- 主分类号: C07K16/00
- IPC分类号: C07K16/00 ; A61K39/395 ; A61K39/40 ; C07K16/24 ; C07K1/00 ; A61K39/00
摘要:
Bispecific antibodies are provided that specifically bind both Tumor Necrosis Factor alpha (TNFα) and Interleukin-17 (IL-17). The bispecific antibodies of the invention are useful for treating various autoimmune diseases, including Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA), and Ankylosing Spondylitis (AS).
公开/授权文献
- US20140255406A1 ANTI-TNF-ANTI-IL-17 BISPECIFIC ANTIBODIES 公开/授权日:2014-09-11
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