Invention Grant
US09423396B2 Bodipy structure fluorescence probes for diverse biological applications
有权
Bodipy结构荧光探针，用于多种生物应用
- Patent Title: Bodipy structure fluorescence probes for diverse biological applications
- Patent Title (中): Bodipy结构荧光探针，用于多种生物应用
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Application No.: US14367596Application Date: 2012-12-20
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Publication No.: US09423396B2Publication Date: 2016-08-23
- Inventor: Young-Tae Chang , Sung Chan Lee , Nam-Young Kang , Seong Wook Yun , Cheryl Kit Mun Leong , Hyung Ho Ha
- Applicant: National University of Singapore , Agency for Science, Technology and Research
- Applicant Address: SG Singapore SG Singapore
- Assignee: National University of Singapore,Agency for Science, Technology and Research
- Current Assignee: National University of Singapore,Agency for Science, Technology and Research
- Current Assignee Address: SG Singapore SG Singapore
- Agency: Hamilton, Brook, Smith & Reynolds, P.C.
- International Application: PCT/SG2012/000483 WO 20121220
- International Announcement: WO2013/095305 WO 20130627
- Main IPC: G01N33/53
- IPC: G01N33/53 ; C07F5/02 ; G01N33/569 ; G01N33/58 ; A61K49/00
Abstract:
The present invention is directed to a fluorescence compound represented by structural Formula (I), with specificity to neural stem cells: (I), or a pharmaceutically acceptable salt thereof. The variables for structural Formula (I) are defined herein. Also described are methods for detection of beta cells, pancreatic islets and microglia cells, comprising using a compound of structural Formula (I) or pharmaceutically acceptable salts thereof. Compounds of structural Formula (I) can also differentiate healthy pancreatic islet cells from diabetic pancreatic islet cells.
Public/Granted literature
- US20140359794A1 BODIPY STRUCTURE FLUORESCENCE PROBES FOR DIVERSE BIOLOGICAL APPLICATIONS Public/Granted day:2014-12-04
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