发明授权
- 专利标题： Process for the preparation of 2 substituted tetrahydropyranols
- 专利标题（中）： 制备2取代四氢吡喃醇的方法
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申请号： US14242956申请日： 2014-04-02
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公开(公告)号： US09428481B2公开(公告)日： 2016-08-30
- 发明人: Gabriele Gralla , Ralf Pelzer
- 申请人： BASF SE
- 申请人地址： DE
- 专利权人： BASF SE
- 当前专利权人： BASF SE
- 当前专利权人地址： DE
- 代理机构： Drinker Biddle & Reath LLP
- 主分类号： C07D309/10
- IPC分类号： C07D309/10
摘要：
The present invention relates to a process for the preparation of 2-substituted 4-hydroxy-4-methyltetrahydropyrans by reacting 3-methylbut-3-en-1-ol (isoprenol) with the corresponding alkenealdehydes in the presence of a strongly acidic ion exchanger with subsequent hydrogenation. Specifically, the present invention relates to a corresponding process for the preparation of 2-isobutyl-4-hydroxy-4-methyltetrahydropyran by reacting isoprenol with prenal, with subsequent hydrogenation.
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