A transmitter's operation is characterized using components having relatively low cost and low complexity. A device includes comparator(s) that compare a transmitter's analog output to predetermined level(s) to generate count(s) associated with analog output range bin(s). Each of the predetermined levels is associated with a corresponding one of the analog output range bins. A transfer function of the transmitter is generated using the comparison count values associated with the analog output range bin(s). A histogram may be generated from the comparison count values associated with the various analog output range bins. An equalizer is implemented to process data that will be transmitted by the transmitter. The equalizer uses equalizer parameter(s) that are selected based on the characterization of the transmitter (e.g., its transfer function, its histogram, etc.). The equalizer may use default or start up parameters until the transmitter's operation is characterized.