Invention Grant
- Patent Title: Detection, prevention, and treatment of anthrax and other infectious diseases
- Patent Title (中): 检测，预防和治疗炭疽等传染病
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Application No.: US13967259Application Date: 2013-08-14
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Publication No.: US09435804B2Publication Date: 2016-09-06
- Inventor: Thomas Kozel , William Murphy , Suzanne Brandt , Bruce R Blazar , Julie A Lovchik , Peter Thorkildson , Ann Percival , C. Rick Lyons
- Applicant: Board of Regents of the Nevada System of Higher Education, on behalf of the University of Nevada , STC.UNM , Regents of the University of Minnesota
- Applicant Address: US NV Reno US MN St. Paul US NM Albuquerque
- Assignee: Board of Regents of the Nevada System of Higher Education, on behalf of the University of Nevada, Reno,Regents of the University of Minnesota,STC UNM
- Current Assignee: Board of Regents of the Nevada System of Higher Education, on behalf of the University of Nevada, Reno,Regents of the University of Minnesota,STC UNM
- Current Assignee Address: US NV Reno US MN St. Paul US NM Albuquerque
- Agency: Klarquist Sparkman, LLP
- Main IPC: G01N33/53
- IPC: G01N33/53 ; A61K39/07 ; A01K39/02 ; G01N33/569
Abstract:
Compositions and methods for the detection, prevention, or treatment of anthrax or other infectious diseases. In one aspect, the present invention provides methods for immunizing humans or animals against Bacillus anthracis or other capsulated pathogens. The methods include administering a capsular polypeptide of a pathogen of interest and a CD40 agonist to a human or animal. The capsular polypeptide or the CD40 agonist is administered in such an amount or frequency that an immunoprotective response can be elicited in the human or animal against the pathogen of interest. In another aspect, the present invention provides methods of using passive immunization with anti-capsular polypeptide antibodies to prevent or treat infections caused by Bacillus anthracis or other pathogens. In yet another aspect, the present invention provides methods useful for diagnosis of anthrax by detection of capsular polypeptide in serum or other biological samples.
Public/Granted literature
- US20150050292A1 Detection, prevention, and treatment of Anthrax and other infectious diseases Public/Granted day:2015-02-19
Information query
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