Invention Grant
US09439948B2 Degradable cage coated with mineral layers for spinal interbody fusion
有权
可剥离的笼子,用于脊椎椎体间融合的矿物层
- Patent Title: Degradable cage coated with mineral layers for spinal interbody fusion
- Patent Title (中): 可剥离的笼子,用于脊椎椎体间融合的矿物层
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Application No.: US11927322Application Date: 2007-10-29
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Publication No.: US09439948B2Publication Date: 2016-09-13
- Inventor: Chia-Ying Lin , Frank LaMarca , William L. Murphy , Scott J. Hollister
- Applicant: Chia-Ying Lin , Frank LaMarca , William L. Murphy , Scott J. Hollister
- Applicant Address: US MI Ann Arbor US WI Madison
- Assignee: The Regents of the University of Michigan,Wisconsin Alumni Research Foundation
- Current Assignee: The Regents of the University of Michigan,Wisconsin Alumni Research Foundation
- Current Assignee Address: US MI Ann Arbor US WI Madison
- Agency: Quarles & Brady LLP
- Main IPC: A61F2/44
- IPC: A61F2/44 ; A61K38/18 ; A61K38/30 ; A61B17/70 ; A61F2/30

Abstract:
A cage for facilitating fusion of bones, such as vertebrae, or fusion of adjacent bone surfaces is disclosed. In one form, the cage includes a plurality of spaced apart walls comprising a biodegradable polymeric material (e.g., polycaprolactone); an osteoconductive mineral coating (e.g., a calcium compound) on at least a portion of the walls; and a bioactive agent (e.g., a bone morphogenetic protein) associated with the polymeric material and/or the coating. The bioactive agent is present in amount that induces ossification between the bones or adjacent bone surfaces. The cage may also include a fixation plate connected to at least one of the walls.
Public/Granted literature
- US20080215093A1 Degradable Cage Coated With Mineral Layers For Spinal Interbody Fusion Public/Granted day:2008-09-04
Information query
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