发明授权
- 专利标题: VEGF antagonist compositions and uses thereof
- 专利标题(中): VEGF拮抗剂组合物及其用途
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申请号: US13814182申请日: 2011-08-05
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公开(公告)号: US09441029B2公开(公告)日: 2016-09-13
- 发明人: James Stefano , Clark Pan , Huawei Qiu , Michael O'Callaghan , Gloria Matthews
- 申请人: James Stefano , Clark Pan , Huawei Qiu , Michael O'Callaghan , Gloria Matthews
- 申请人地址: US MA Cambridge
- 专利权人: Genzyme Corporation
- 当前专利权人: Genzyme Corporation
- 当前专利权人地址: US MA Cambridge
- 代理机构: Robins Law Group
- 代理商 Roberta L. Robins
- 国际申请: PCT/US2011/046802 WO 20110805
- 国际公布: WO2012/019128 WO 20120209
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07K14/435 ; C07K14/71 ; C12N9/12
摘要:
The invention provides compositions and methods for treating a disease or disorder associated with vascular endothelial growth factor (VEGF). Specifically, the invention relates to an oligomerized VEGF binding domain to provide VEGF antagonism, and thereby treat diseases associated thereof.
公开/授权文献
- US20130324465A1 VEGF ANTAGONIST COMPOSITIONS AND USES THEREOF 公开/授权日:2013-12-05
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