发明授权
- 专利标题： Schiff bases of thiazoles: a new class of ureases inhibitors
- 专利标题（中）： 噻唑的席夫碱：一类新的脲酶抑制剂
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申请号： US14310738申请日： 2014-06-20
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公开(公告)号： US09447057B2公开(公告)日： 2016-09-20
- 发明人: Muhammad Iqbal Choudhary , Ajmal Khan , Khalid M. Khan , Nida Ambreen , Atia-tul Wahab , Atta-ur Rahman
- 申请人： Muhammad Iqbal Choudhary , Ajmal Khan , Khalid M. Khan , Nida Ambreen , Atia-tul Wahab , Atta-ur Rahman
- 代理商 Sarfaraz K. Niazi
- 主分类号： A61K31/40
- IPC分类号： A61K31/40 ; A61K31/44 ; C07D277/42 ; C07D417/12 ; C07D401/12 ; A61K31/427 ; A61K31/4439
摘要：
One embodiment of the invention relates to treating diseases associated with increased urease enzyme activity comprising administering an effective amount of a compound selected from a group consisting of 28 thiazoles Schiff bases. Kinetic studies were performed on ten (10) of the most active compounds.
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