发明授权
- 专利标题: Imidazopyridine compounds
- 专利标题(中): 咪唑并吡啶化合物
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申请号: US14090074申请日: 2013-11-26
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公开(公告)号: US09447090B2公开(公告)日: 2016-09-20
- 发明人: Yuji Koga , Kyoichi Maeno , Ippei Sato , Yoshimasa Imamura , Takeshi Hanazawa , Maiko Iida , Kazuhiko Ohne , Kenichiro Imamura , Tsubasa Watanabe , Eisuke Nozawa , Hiroshi Shibata
- 申请人: Astellas Pharma Inc.
- 申请人地址: JP Tokyo
- 专利权人: Astellas Pharma Inc.
- 当前专利权人: Astellas Pharma Inc.
- 当前专利权人地址: JP Tokyo
- 代理商 Amy H. Fix
- 优先权: JP2011-119826 20110530; JP2011-287682 20111228
- 主分类号: C07D471/04
- IPC分类号: C07D471/04 ; C07D453/02 ; C07D519/00
摘要:
An excellent drug for treating or preventing cardiovascular diseases, based on cGMP production enhancing action due to soluble guanylate cyclase activating action, is provided. It was found that imidazopyridine compounds having a carbamoyl group at the 3-position and a substituent bonded at the 8-position via an oxygen atom in an imidazo[1,2-a]pyridine skeleton exhibits a cGMP production enhancing action by a potent soluble guanylate cyclase activating action, and is useful as a drug for treating or preventing various soluble guanylate cyclase-related cardiovascular diseases, thereby completing the present invention.
公开/授权文献
- US20140088080A1 IMIDAZOPYRIDINE COMPOUNDS 公开/授权日:2014-03-27
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