发明授权
- 专利标题: Method for producing induced pluripotent stem cells
- 专利标题(中): 诱导多能干细胞的制备方法
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申请号: US13641370申请日: 2011-04-15
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公开(公告)号: US09447432B2公开(公告)日: 2016-09-20
- 发明人: Keiichi Fukuda , Shinsuke Yuasa , Tomohisa Seki , Mamoru Hasegawa
- 申请人: Keiichi Fukuda , Shinsuke Yuasa , Tomohisa Seki , Mamoru Hasegawa
- 申请人地址: JP Tokyo JP Ibaraki
- 专利权人: Keio University,DNAVEC Corporation
- 当前专利权人: Keio University,DNAVEC Corporation
- 当前专利权人地址: JP Tokyo JP Ibaraki
- 代理机构: Clark & Elbing LLP
- 优先权: JP2010-095404 20100416
- 国际申请: PCT/JP2011/059429 WO 20110415
- 国际公布: WO2011/129446 WO 20111020
- 主分类号: C12N15/86
- IPC分类号: C12N15/86 ; C12N5/074
摘要:
An object of the present invention is to provide methods for producing iPS cells with low invasivity and high efficiency. The iPS cells can be produced with high efficiency using a method comprising the steps of culturing mononuclear cells derived from peripheral blood for 3 to 14 days in the presence of anti-CD3 antibody, and subjecting the cultured mononuclear cells to dedifferentiation.
公开/授权文献
- US20130189786A1 METHOD FOR PRODUCING INDUCED PLURIPOTENT STEM CELLS 公开/授权日:2013-07-25
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