发明授权
US09452227B2 Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments
有权
使用抗IL-6抗体或片段治疗或诊断与升高的IL-6相关的病症的方法
- 专利标题： Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments
- 专利标题（中）： 使用抗IL-6抗体或片段治疗或诊断与升高的IL-6相关的病症的方法
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申请号： US12624778申请日： 2009-11-24
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公开(公告)号： US09452227B2公开(公告)日： 2016-09-27
- 发明人: Leon Garcia-Martinez , Anne Elisabeth Carvalho Jensen , Katie Olson , Ben Dutzar , John Latham , Brian Kovacevich , Jeffrey T. L. Smith , Mark Litton , Randall Schatzman
- 申请人： Leon Garcia-Martinez , Anne Elisabeth Carvalho Jensen , Katie Olson , Ben Dutzar , John Latham , Brian Kovacevich , Jeffrey T. L. Smith , Mark Litton , Randall Schatzman
- 申请人地址： US NV Las Vegas
- 专利权人： ALDERBIO HOLDINGS LLC
- 当前专利权人： ALDERBIO HOLDINGS LLC
- 当前专利权人地址： US NV Las Vegas
- 代理机构： LeClairRyan, A Professional Corporation
- 代理商 Robin L. Teskin
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/24 ; A61K51/10 ; A61K49/00 ; A61K39/00 ; C12P21/08 ; C12N15/63
摘要：
The invention relates to the use of anti-IL-6 antibodies or antibody fragments containing a specific epitopic specificity to treat conditions involving elevated Il-6. In some embodiments the anti-IL-6 antibodies contain specific CDRs.
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